What clinical sign is commonly associated with Rickets?

The common clinical sign associated with Rickets is the bowing of long bones. Rickets is a disorder that arises due to a deficiency of vitamin D, calcium, or phosphate, leading to impaired bone mineralization. This deficiency particularly affects the growing bones in children, and as the bones soften, they become malleable. This malleability causes deformities such as bowing of the long bones, especially in weight-bearing areas, as the increased physical stress cannot be adequately supported by the weakened bone structure.

In contrast, increased bone density is not characteristic of Rickets; in fact, Rickets typically involves a reduction in mineral density. Joint swelling can occur due to various reasons but is not a hallmark sign of Rickets itself. Delayed growth milestones can be associated with several conditions, including those unrelated to Rickets. However, the distinguishing feature that directly reflects the impact of Rickets on bone structure is the bowing of long bones.